• 1-pentyl-1H-indole

1-pentyl-1H-indole

  • CasNo：59529-21-4
  • Purity：99%

Product Details;

CasNo： 59529-21-4

Molecular Formula： C13H17N

Buy High Quality High Purity 1-pentyl-1H-indole 59529-21-4 with Great Price

  • Molecular Formula:C13H17N
  • Molecular Weight:187.285
  • Boiling Point:302.2 °C at 760 mmHg 
  • Flash Point:136.6 °C 
  • PSA：4.93000 
  • Density:0.96 g/cm3 
  • LogP:3.83150 

1-pentyl-1H-indole(Cas 59529-21-4) Usage

Uses

1-Pentyl-1H-indole is a chemical compound that belongs to the class of compounds known as indoles. 1-Pentyl-1H-indole, or AM-2201, is a synthetic cannabinoid that was initially developed as a research chemical for studying the endocannabinoid system. It is structurally related to cannabinoids found in the cannabis plant and was created for use in scientific research to better understand the interaction of cannabinoids with the human body.

InChI:InChI=1/C8H5BrFN/c9-4-7-3-8(10)2-1-6(7)5-11/h1-3H,4H2

59529-21-4 Relevant articles

New-generation azaindole-adamantyl-derived synthetic cannabinoids

Longworth, Mitchell,Reekie, Tristan A.,Blakey, Karen,Boyd, Rochelle,Connor, Mark,Kassiou, Michael

, p. 350 - 365 (2019)

Purpose: This work reports the synthesis...

Palladium-Catalyzed Three-Component Regioselective Dehydrogenative Coupling of Indoles, 2-Methylbut-2-ene, and Carboxylic Acids

Guo, Rui-Li,Jia, Qiong,Wang, Meng-Yue,Wang, Yong-Qiang,Yang, Jin-Hui,Zhang, Xing-Long,Zhao, Bao-Yin

supporting information, p. 9574 - 9579 (2021/12/14)

Five-carbon (C5) structural units are th...

Exploring Stereochemical and Conformational Requirements at Cannabinoid Receptors for Synthetic Cannabinoids Related to SDB-006, 5F-SDB-006, CUMYL-PICA, and 5F-CUMYL-PICA

Ametovski, Adam,Macdonald, Christa,Manning, Jamie J.,Haneef, S. A. Syed,Santiago, Marina,Martin, Lewis,Sparkes, Eric,Reckers, Andrew,Gerona, Roy R.,Connor, Mark,Glass, Michelle,Banister, Samuel D.

, p. 3672 - 3682 (2020/11/18)

Synthetic cannabinoid receptor agonists ...

Tryptamine Synthesis by Iron Porphyrin Catalyzed C?H Functionalization of Indoles with Diazoacetonitrile

Hock, Katharina J.,Knorrscheidt, Anja,Hommelsheim, Renè,Ho, Junming,Weissenborn, Martin J.,Koenigs, Rene M.

supporting information, p. 3630 - 3634 (2019/02/13)

The functionalization of C?H bonds with ...

59529-21-4 Process route

indole
120-72-9

indole

1-Bromopentane
110-53-2

1-Bromopentane

1-pentyl-1H-indole
59529-21-4

1-pentyl-1H-indole

Conditions
Conditions Yield
indole; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 0.5h;
1-Bromopentane; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃;
100%
indole; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 5 - 20 ℃; Inert atmosphere;
1-Bromopentane; In N,N-dimethyl-formamide; mineral oil; at 5 - 20 ℃; for 16h; Inert atmosphere;
95%
With potassium hydroxide; tetrabutylammomium bromide; potassium carbonate; for 0.0075h; microwave irradiation (300 W);
86%
indole; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 0.166667h; Inert atmosphere;
1-Bromopentane; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; Inert atmosphere;
80%
With sodium hydride; Yield given. Multistep reaction; 1.) DMF, 90 min, 2.) 50-55 deg C, 36 h;
 
indole; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;
1-Bromopentane; In N,N-dimethyl-formamide; at 0 ℃;
 
indole; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; for 0.166667h; Cooling with ice; Inert atmosphere;
1-Bromopentane; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 1h; Cooling with ice; Inert atmosphere;
 
indole; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.5h; Inert atmosphere;
1-Bromopentane; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1h; Inert atmosphere;
 
indole; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 0.5h;
1-Bromopentane; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃;
 
indole
120-72-9

indole

amyl iodide
628-17-1

amyl iodide

1-pentyl-1H-indole
59529-21-4

1-pentyl-1H-indole

Conditions
Conditions Yield
With triethylamine; In acetonitrile; at 80 ℃; for 16h;
75%

59529-21-4 Upstream products

  • 120-72-9
    120-72-9

    indole

  • 110-53-2
    110-53-2

    1-Bromopentane

  • 693-03-8
    693-03-8

    n-butyl magnesium bromide

  • 124337-33-3
    124337-33-3

    1-(1H-benzotriazol-1-yl-methyl)-1H-indole

59529-21-4 Downstream products

  • 824960-64-7
    824960-64-7

    (7-ethyl-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)methanone

  • 824959-81-1
    824959-81-1

    JWH-210

  • 824960-02-3
    824960-02-3

    (1-pentyl-1H-indol-3-yl)(4-propyl-1-naphthalenyl)methanone

  • 824960-76-1
    824960-76-1

    (2-methoxy-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)methanone

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