CasNo： 81409-90-7
Molecular Formula： C26H37N5O2
Appearance： White crystalline solid
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Cabergoline is White crystalline solid, while it's Molecular Formula is C26H37N5O2. Cabergoline is an ergot derivative and a dopamine D2-receptor agonist (1,2,3). It inhibits the secretion of prolactin and growth hormone.
The CAS number of Cabergoline is 81409-90-7.
More information of Cabergoline 81409-90-7 are:
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Synonyms |
Ergoline-8-carboxamide,N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-, (8b)- (9CI);Cabaser;Cabaseril;1-((6-Allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea;Ergoline-8beta-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-; |
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CAS Number |
81409-90-7 |
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Molecular Formula |
C26H37N5O2 |
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Molecular Weight |
451.612 |
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Density |
1.156 g/cm3 |
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Melting Point |
102-104°C |
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HS CODE |
2939690000 |
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PSA |
71.68000 |
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LogP |
3.52270 |
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Pka |
13.05±0.46(Predicted) |
Cabergoline is a potent, selective, and long-lasting dopamine D2 receptor agonist launched in 1993 in Belgium as a prolactin inhibitor. A single 1 mg dose of cabergoline effectively prevents puerperal lactation for up to 14 days, remarkably superior to other drugs that require a daily regimen. It has a low rate of rebound breast activity and good tolerability. Cabergoline is also in clinical trials for Parkinson's disease, breast cancer, and hyperprolactinaemia.
InChI:InChI=1/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33)/t19-,21?,23-/m1/s1
Articles related to Cabergoline:
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Article |
Source |
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New and efficient process for the preperation of cabergoline and its intermediates |
- Page/Page column 12, (2008/12/08) |
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PROCESS FOR THE PREPARATION OF AMORPHOUS CABERGOLINE |
- Page/Page column 4,5, (2008/12/07) |
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