CasNo： 107868-30-4
Molecular Formula： C20H24O2
Appearance： white to light yellow crystal powder
Fast Delivery High Quality Aromasin(Exemestane) 107868-30-4 with Best Price We supply high quality Exemestane (CAS 107868-30-4), in stock, factory directly supply to clients, lower prices, more competitiveness.
Exemestane is white to light yellow crystal powder, while it's Molecular Formula is C20H24O2. Labeled Exemestane, intended for use as an internal standard for the quantification of Exemestane by GC- or LC-mass spectrometry.
The CAS number of Exemestane is 107868-30-4.
More information of Exemestane 107868-30-4 are:
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Synonyms |
Exemestane [USAN:INN:BAN];Aromasil;Aromasin;FCE 24304;Exemestane Tablets;Androsta-1,4-diene-3,17-dione, 6-methylene-;Exemestano;Exemestano [INN-Spanish];Exemestanum;Exemestanum [INN-Latin];HSDB 7463;Exemestane; |
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CAS Number |
107868-30-4 |
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Molecular Formula |
C20H24O2 |
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Molecular Weight |
296.409 |
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Density |
1.13 g/cm3 |
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Melting Point |
155.13 ºC |
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Boiling Point |
453.7 ºC at 760 mmHg |
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Flash Point |
169 ºC |
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HS CODE |
29372900 |
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PSA |
34.14000 |
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LogP |
4.02950 |
Exemestane is a medication used in the United States for specific medical purposes. Its primary use is related to the treatment of hormone receptor-positive breast cancer, particularly in postmenopausal women. Here are its main uses:
Breast Cancer Treatment: Exemestane is primarily prescribed as an adjuvant treatment for postmenopausal women with early-stage breast cancer. It is often recommended following surgery, radiation, or other therapies to reduce the risk of cancer recurrence. Exemestane works by inhibiting the production of estrogen in the body, as estrogen can promote the growth of hormone receptor-positive breast tumors.
Advanced Breast Cancer: In cases of advanced or metastatic breast cancer, where the cancer has spread to other parts of the body, Exemestane may be used to slow down the progression of the disease. It is commonly prescribed when other hormonal therapies have not been effective.
InChI:InChI=1/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14?,15?,16?,19-,20+/m1/s1
Articles related to Exemestane:
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Article |
Source |
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Increased yield of biotransformation of exemestane with β-cyclodextrin complexation technique |
Li, Guang,Li, Fushuang,Deng, Le,Fang, Xiaolan,Zou, Hui,Xu, Kangpin,Li, Tian,Tan, Guishan , p. 1148 - 1151 (2013) |
| Exemestane for Breast-Cancer Prevention in Postmenopausal Women |
List of authors. Paul E. Goss, M.D., Ph.D., James N. Ingle, M.D., José E. Alés-Martínez, M.D., Ph.D., Angela M. Cheung, M.D., Ph.D., Rowan T. Chlebowski, M.D., Ph.D., Jean Wactawski-Wende, Ph.D., Anne McTiernan, M.D., John Robbins, M.D., Karen C. Johnson, M.D., M.P.H., Lisa W. Martin, M.D., Eric Winquist, M.D., Gloria E. Sarto, M.D., Judy E. Garber, M.D., Carol J. Fabian, M.D., Pascal Pujol, M.D., Elizabeth Maunsell, Ph.D., Patricia Farmer, M.D., Karen A. Gelmon, M.D., Dongsheng Tu, Ph.D., and Harriet Richardson, Ph.D. , N Engl J Med 2011; 364:2381-2391 |
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1,2-Dehydrogenation of steroidal 6-methylen derivatives. Synthesis of exemestane |
Marcos-Escribano, Andrés,Bermejo, Francisco A.,Bonde-Larsen, Antonio Lorente,Retuerto, Jesús Iglesias,Sierra, Ignacio Herráiz , p. 7587 - 7590 (2009) |
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