What is the Articaine?

Articaine is White or white crystalline powder, while it's Molecular Formula is C13H20N2O3S. White or white crystalline powder Articaine is an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand , food surgery and in dentistry.

What is the CAS number for Articaine?

The CAS number of Articaine is 23964-58-1.

What is Articaine (23964-58-1) used for?

Articaine [4-methyl-3-(2-propylaminopropionamido) thiophene-2-carboxylic acid methyl esterhydrochloride] has been widely used in dentistry since its approval by the U.S. FDA in the year2000 because of its quick onset and short duration of action. The structure of articaine differsfrom those of all other amino amide-type local anesthetics in that it contains a thiophene ringinstead of a benzene ring and a carbomethoxy group. This renders the molecule more lipophilicand, thus, easier to cross any lipoidal membranes.Its local anesthetic potency is approximately 1.5-fold that of lidocaine, even though it has similarpKa (7.8) and plasma protein binding (76%) properties. Articaine also is metabolized primarily byplasma cholinesterases because of the presence of an ester group and, therefore, has a muchshorter duration of action than lidocaine (i.e., only approximately one-fourth that of lidocaine).Articaine undergoes rapid hydrolysis of the carbomethoxy group to give articainic acid, which iseliminated either unchanged (75%) or as its glucuronides (25%). Compared with to other shortacting, amino amide-type local anesthetics, such as mepivacaine, lidocaine, or prilocaine,articaine is said to be a much safer drug for regional anesthesia and is the drug of choice fordental procedures.InChI:InChI=1/C13H20N2O3S/c1-5-6-14-9(3)12(16)15-10-8(2)7-19-11(10)13(17)18-4/h7,9,14H,5-6H2,1-4H3,(H,15,16)

Factory Sells High Grade Articaine Base 23964-58-1 with Chinese Supplier

Product Details;

CasNo： 23964-58-1

Molecular Formula： C₁₃H₂₀N₂O₃S

Appearance： White or white crystalline powder