• Mepivacaine HCl

Mepivacaine HCl

  • CasNo:1722-62-9
  • Purity:99%

Product Details;

CasNo: 1722-62-9

Molecular Formula: C15H22N2O.HCl

Appearance: White or off white crystalline powder

Buy High Quality Mepivacaine HCl 1722-62-9 White Crystalline Powder with Good Supplier In China

  • Molecular Formula:C15H22N2O.HCl
  • Molecular Weight:282.813
  • Appearance/Colour:White or off white crystalline powder 
  • Vapor Pressure:4.52E-06mmHg at 25°C 
  • Melting Point:255-257oC (dec.) 
  • Boiling Point:383.1 °C at 760 mmHg 
  • Flash Point:185.5 °C 
  • PSA:32.34000 
  • LogP:3.53910 

Mepivacaine HCl (Cas 1722-62-9) Usage

Chemical Properties

White Solid

Uses

Mepivacaine HCl, is a local anesthetic widely utilized in the United States for its pain-relieving properties. It is primarily administered by healthcare professionals, particularly in dentistry and minor surgical procedures, to provide temporary and localized anesthesia by blocking nerve signals in the targeted area. It is generally considered safe when used as directed by healthcare professionals in the United States.

Definition

ChEBI: The hydrochloride salt of mepivacaine. It is used as a local anaesthetic.

Brand name

Arestocaine Hydrochloride (Solvay Pharmaceuticals); Carbocaine (Hospira); Isocaine Hydrochloride(Novocol); Polocaine (AstraZeneca); Polocaine (Dentsply); Scandonest (Deproco).

Biochem/physiol Actions

Local anesthetic. Reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current. Blocks tandem pore (TASK) and Kv1.5, potassium channels in model systems.

Safety Profile

skin irritant. Questionable carcinogen with

InChI:InChI=1/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H

1722-62-9 Relevant articles

Anti-inflammatory and analgesic effects of intra-articular injection of triamcinolone acetonide, mepivacaine hydrochloride, or both on lipopolysaccharide-induced lameness in horses

Alastair T. Kay BVSc, David M. Bolt Dr med vet, MS, Akikazu Ishihara BVSc, Paivi J. Rajala-Schultz DVM, PhD, and Alicia L. Bertone DVM, PhD

, American Journal of Veterinary Research, Volume 69: Issue 12

Treatment with TA also induced higher WBC counts and mepivacaine concentrations in synovial fluid, compared with results for mepivacaine alone.

Effects of triamcinolone acetonide, sodium hyaluronate, amikacin sulfate, and mepivacaine hydrochloride, alone and in combination, on morphology and matrix composition of lipopolysaccharide-challenged and unchallenged equine articular cartilage explants

David M. Bolt Dr med vet, MS, Akikazu Ishihara BVSc, Stephen E. Weisbrode VMD, PhD, and Alicia L. Bertone DVM, PhD

, American Journal of Veterinary Research, Volume 69: Issue 7

Mepivacaine hydrochloride in combination with LPS caused an increase in empty lacunae and pyknotic nuclei (P < 0.001), which included the deeper cartilage zones. Mepivacaine hydrochloride amplified the negative influence of LPS on chondrocytes.

1722-62-9 Downstream products

  • 345261-08-7
    345261-08-7

    2-{[(2,6-Dimethylphenyl)amino]carbonyl}-1,1-dimethylpiperidinium iodide

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