CasNo： 15262-86-9
Molecular Formula： C25H38O3
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Description |
Testosterone isocaproate is a testosterone ester with improved bioavailability and metabolic half life compared to the endogenous hormone.It used to testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis. |
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Chemical Properties |
White or almost white powder. |
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Uses |
Testosterone Isocaproate is used in the treatment of male hypogonadism (a condition in which the body does not produce enough testosterone). |
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Definition |
ChEBI: Testosterone isocaproate is a steroid ester. |
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Mode of action |
Testosterone Isocaproate is similar to the natural male hormone, testosterone. Testosterone binds to the androgen receptor (AR), and the ligand-receptor complex translocates to the nucleus and binds to androgen response elements (AREs) on chromosomal DNA, thereby modulating transcription of a set of androgen-responsive genes. Testosterone can also be converted to estrogen and has a similar regulatory action on genes containing estrogen response elements (EREs). |
InChI:InChI=1/C25H38O3/c1-16(2)5-10-23(27)28-22-9-8-20-19-7-6-17-15-18(26)11-13-24(17,3)21(19)12-14-25(20,22)4/h15-16,19-22H,5-14H2,1-4H3/t19-,20-,21-,22-,24-,25-/m0/s1
3β-Hydroxy-17β-oxyisocapronyl-androsten
Testosterone isocaproate
| Conditions | Yield |
|---|---|
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With
cyclohexanone; aluminum isopropoxide;
In
toluene;
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4-Methylpentanoic acid
Testosterone isocaproate
| Conditions | Yield |
|---|---|
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Multi-step reaction with 3 steps
1: (i) PhSO2Cl, Py, (ii) /BRN= 2510253/
2: KOH / methanol; CH2Cl2
3: Al(OiPr)3, cyclohexanone / toluene
With
potassium hydroxide; cyclohexanone; aluminum isopropoxide;
In
methanol; dichloromethane; toluene;
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3β-Hydroxy-17β-oxyisocapronyl-androsten
4-Methylpentanoic acid
4-Methyl-pentanoic acid (3S,8R,9S,10R,13S,14S,17S)-3-acetoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester
androstenediol-3-acetate