• Acetaminophen

Acetaminophen

  • CasNo:103-90-2
  • Purity:99%

Product Details;

CasNo: 103-90-2

Molecular Formula: C8H9NO2

Appearance: White crystalline powder

Quality products make an important contribution to long-term revenue and profitability. Best Price Acetaminophen 103-90-2 in stock Cheapest Price

1.What is the 4-Acetamidophenol ?

Acetaminophen (Tylenol) is an effective antipyretic and analgesic that is well tolerated at therapeutic doses. It has only weak antiinflammatory activity; thus, it is not useful in the treatment of rheumatoid arthritis and other inflammatory conditions.

Acetaminophen is widely used as an analgesic and fever-reducing agent. Acetaminophen is designed for moderate analgesia. It is also effective like aspirin and is used in analgesia for headaches (from weak to moderate pain), myalgia, arthralgia, chronic pain, for oncological and post-operational pain, etc.

glutathion
70-18-8

glutathion

N-acetyl-p-benzoquinoneimine
50700-49-7

N-acetyl-p-benzoquinoneimine

4-acetaminophenol
103-90-2,8055-08-1

4-acetaminophenol

S-(5'-Acetamido-2'-hydroxyphenyl)glutathion
64889-81-2

S-(5'-Acetamido-2'-hydroxyphenyl)glutathion

Conditions
Conditions Yield
In water; benzene; at 37 ℃; Product distribution;
4-Hydroxyacetophenone
99-93-4

4-Hydroxyacetophenone

N-Methyl 4-hydroxy benzamide
27642-27-9

N-Methyl 4-hydroxy benzamide

4-acetaminophenol
103-90-2,8055-08-1

4-acetaminophenol

4-hydroxyacetophenone oxime
34523-34-7

4-hydroxyacetophenone oxime

Conditions
Conditions Yield
With hydroxylamine sulfate; at 80 ℃; for 2.5h;
85%
15%
With hydroxylamine sulfate; at 80 ℃; for 2.5h;
15%
83%

2.What is the CAS number for 4-Acetamidophenol ?

The CAS number of 4-Acetamidophenol is 103-90-2.

More information of 4-Acetamidophenol 103-90-2 are:

CAS Number

103-90-2

Density

1.249 g/cm3

Melting Point

168-172 °C(lit.)

Boiling Point

387.8 °C at 760 mmHg

Flash Point

188.4 °C

Vapor Pressure

0.008Pa at 25℃

Refractive Index

1.5810 (rough estimate)

HS CODE

2924.29

PSA

49.33000

LogP

1.42360

Pka

9.86±0.13(Predicted)

3.What are another words for 4-Acetamidophenol ?

Synonyms for 4-Acetamidophenol 103-90-2:Acetamide,N-(4-hydroxyphenyl)-;Acetanilide,4'-hydroxy- (7CI,8CI);4-(Acetylamino)phenol;4-(N-Acetylamino)phenol;4-Acetamidophenol;4-Acetaminophenol;4-Hydroxyacetanilide;4'-Hydroxyacetanilide;Alpiny;Alvedon;Anhiba;Apamid;Apamide;Banesin;Ben-u-ron;Bickie-mol;Biocetamol;Cetadol;Clixodyne;Daphalgan;Datril;Dirox;Enelfa;Eu-Med;Exdol;Gattaphen T;Homoolan;Jin Gang;Korum;Lestemp;Liquagesic;Lonarid;Lyteca;Lyteca Syrup;Minoset;Minoset Plus;Momentum;Multin;N-(4-Hydroxyphenyl)acetamide;N-Acetyl-4-aminophenol;N-Acetyl-4-hydroxyaniline;Pacemo;Pacemol;Panadol;Panadol Actifast;Panadol Extend;Panaleve;Panasorb;Panets;Panodil;Paracetamol;Paracetamol DC;Paracetamole;Parageniol;Paralen;Paramol;Paraspen;Parelan;Parmol;Pasolind N;Pedric;k*e*t*a*m*i*n*e ,kush available;

4.What is the molecular formula of 4-Acetamidophenol?

The chemical formula of  4-Acetamidophenol is C8H9NO2 which containing 8 Carbon atoms,9 Hydrogen atoms,1 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of  4-Acetamidophenol is 151.165.

5.What is 4-Acetamidophenol (103-90-2) used for?

Acetaminophen is an analgesic and antipyretic compound. Unlike many NSAIDs, which inhibit both COX-1 and COX-2, early studies suggested that acetaminophen is a poor inhibitor of both isoforms. However, it does inhibit COX-2 by 83% and COX-1 by 56% in human blood ex vivo, albeit at a high 1,000 mg dose, with IC50 values of 25.8 and 113.7 μM, respectively. Acetaminophen is enzymatically and non-enzymatically converted to several reactive metabolites that contribute to adverse or indirect effects, including liver injury. At toxic doses, the acetaminophen metabolite N-acetyl-4-benzoquinone imine (NAPQI; ) depletes glutathione reserves in the liver, leading to an accumulation of NAPQI and subsequent hepatocyte necrosis. Acetaminophen decreases glutathione levels and reduces glutathione peroxidase activity in mice when administered at a dose of 250 mg/kg and induces ferroptotic cell death in primary mouse hepatocytes, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 . Acetaminophen has analgesic and antipyretic properties in animal models.

InChI:InChI=1/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)/i2D,3D,4D,5D

Relevant articles related to 4-Acetamidophenol:

Article

Source

Influence of medium and temperature on the hydrolysis kinetics of propacetamol hydrochloride: Determination using derivative spectrophotometry

Barcia, Emilia,Martin, Alicia,Azuara, Ma. Luz,Negro, Sofia

, p. 277 - 280 (2005)

Subphthalocyanines: Addressing water-solubility, nano-encapsulation and activation for optical imaging of B16 melanoma cells

Bernhard, Yann,Winckler, Pascale,Chassagnon, Remi,Richard, Philippe,Gigot, lodie,Perrier-Cornet, Jean-Marie,Decrau, Richard A.

, p. 13975 - 13978 (2014)

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