CasNo： 73-78-9
Molecular Formula： C14H22N2O.HCl
Appearance： white crystal powder
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The drug can be used for infiltration anesthesia, epidural anesthesia, surface anesthesia and nerve conduction block The drug can be used for acute myocardial infarction after ventricular premature beats and ventricular tachycardia, and for digitalis poisoning, cardiac surgery and ventricular arrhythmias caused by cardiac catheterization. But it is usually ineffective for supraventricular arrhythmias.
Anesthetic (local); antiarrhythmic (class IB). Long-acting, membrane stabilizing agent against ventricular arrhythmia. Originally developed as a local anesthetic.
2-diethylamino-N-(2,6-dimethylphenyl)-acetamide
lidocaine hydrochloride
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
diethyl ether;
|
100% |
|
With
hydrogenchloride; pyrographite;
In
water; 1,2-dichloro-ethane;
for 0.333333h;
pH=3.5;
pH-value;
|
88.72% |
|
With
hydrogenchloride;
In
water; acetone;
at 20 ℃;
pH=<= 4;
|
80.6% |
diethylamine
chloroacetyl chloride
2,6-dimethylaniline
lidocaine hydrochloride
| Conditions | Yield |
|---|---|
|
chloroacetyl chloride; 2,6-dimethylaniline;
In
1-methyl-pyrrolidin-2-one; methanol; water;
at 120 ℃;
for 0.306667h;
Flow reactor;
diethylamine;
With
potassium hydroxide;
In
methanol; water;
at 130 ℃;
for 0.295h;
under 12751.3 Torr;
Flow reactor;
With
hydrogenchloride;
In
methanol; diethyl ether; water;
|
The CAS number of Lidocaine hydrochloride is 73-78-9.
More information of Lidocaine hydrochloride 73-78-9 are:
|
CAS Number |
73-78-9 |
|
Melting Point |
80-82 °C |
|
Boiling Point |
350.8 °C at 760 mmHg |
|
Flash Point |
166 °C |
|
Vapor Pressure |
4.28E-05mmHg at 25°C |
|
HS CODE |
2924299090 |
|
PSA |
32.34000 |
|
LogP |
3.45870 |
Synonyms for Lidocaine hydrochloride 73-78-9:2',6'-Acetoxylidide,2-(diethylamino)-, monohydrochloride (8CI);Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-,monohydrochloride (9CI);2-(Diethylamino)-2',6'-dimethylacetanilide hydrochloride;Alphacaine;DioCaine;Irtopan;Lidesthesin;Lidocain hydrochloride;Lidocaine monohydrochloride;Lidothesin;Lignavet;Luan;Metaclopromide hydrochloride;Odontalg;Proliferol;Sedagul;Versicane;Xylocaine Astra;Xylocard;Xylotox;Lidocaine HCl .1H2O;
The chemical formula of Lidocaine hydrochloride is C14H22N2O.HCl which containing 14 Carbon atoms,23 Hydrogen atoms,2 Nitrogen atoms and 1 Chlorine atoms,and the molecular weight of Lidocaine hydrochloride is 270.802.
InChI:InChI=1/C14H22N2O.ClH/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H
Relevant articles related to Lidocaine hydrochloride:
|
Article |
Source |
|
Preparation method of lidocaine hydrochloride |
- Paragraph 0031; 0037-0038, (2020/01/25) |
|
On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system |
Adamo, Andrea,Beingessner, Rachel L.,Behnam, Mohsen,Chen, Jie,Jamison, Timothy F.,Jensen, Klavs F.,Monbaliu, Jean-Christophe M.,Myerson, Allan S.,Revalor, Eve M.,Snead, David R.,Stelzer, Torsten,Weeranoppanant, Nopphon,Wong, Shin Yee,Zhang, Ping , p. 61 - 67 (2016/04/26) |
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