Chinese Manufacturer Supply Lidocaine Base 137-58-6 Efficient Transportation, Good Supplier In China

Q: What is the Lidocaine?

Lidocaine is solid, while it's Molecular Formula is C14H22N2O. solid Antiarrhythmic Agents, Anesthetics；Anticonvulsant；antihypertensive

Q: What is Lidocaine (137-58-6) used for?

Lidocaine [2-(diethylamino)-N-(2, 6-dimethylphenyl) acetamide monohydrochloride] is the mostcommonly used amino amide-type local anesthetic. Lidocaine is very lipid soluble and, thus, hasa more rapid onset and a longer duration of action than most amino ester-type local anesthetics,such as procaine and tetracaine. It can be administered parenterally (with or without epinephrine)or topically either by itself or in combination with prilocaine or etidocaine as a eutectic mixturethat is very popular with pediatric patients. The use of lidocaine–epinephrine mixtures should beavoided, however, in areas with limited vascular supply to prevent tissue necrosis. Lidocaine alsofrequently is used as a class IB antiarrhythmic agent for the treatment of ventricular arrhythmias,both because it binds and inhibits sodium channels in the cardiac muscle and because of itslonger duration of action than amino ester-type local anesthetics.Central nervous system changes are the most frequently observed systemic toxicities oflidocaine. The initial manifestations are restlessness, vertigo, tinnitus, slurred speech, andeventually, seizures. Subsequent manifestations include CNS depression with a cessation ofconvulsions and the onset of unconsciousness and respiratory depression or cardiac arrest. Thisbiphasic effect occurs because local anesthetics initially block the inhibitory GABAergicpathways, resulting in stimulation, and eventually block both inhibitory and excitatory pathways (i.e., block the sodium channels associated with the NMDA receptors, resulting in overall CNS inhibition).InChI:InChI=1/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)/p+1

Quality products make an important contribution to long-term revenue and profitability. Chinese Manufacturer Supply Lidocaine Base 137-58-6 Efficient Transportation, Good Supplier In China.

1.What is the Lidocaine ?

Lidocaine is a synthetic local anesthetic and antiarrhythmic medication that belongs to the amide class of anesthetics.

: 178421-96-0
C₁₄H₂₂N₂O*C₅₆H₉₈O₃₅

: 137-58-6
2-diethylamino-N-(2,6-dimethylphenyl)-acetamide

: 51166-71-3
heptakis(2,6-di-O-methyl)cyclomaltoheptaose

Conditions

Conditions	Yield
With pluronic copolymer F₂₉₀; In water; at 25 ℃; Reagent/catalyst; Equilibrium constant;

: [(2,6-dimethylphenylcarbamoyl)methyl]diethyl-(4-phosphonooxybenzyl)ammonium trifluoroacetate disodium salt

: 623-05-2
(4-hydroxyphenyl)methanol

: 137-58-6
2-diethylamino-N-(2,6-dimethylphenyl)-acetamide

Conditions

Conditions	Yield
With alkaline phosphatase; In water; at 37 ℃; for 6h; pH=7.4; Enzyme kinetics; Enzymatic reaction;

2.What is the CAS number for Lidocaine ?

The CAS number of Lidocaine is 137-58-6.

Chinese Manufacturer Supply 137-58-6. More information of Lidocaine 137-58-6 are:

CAS Number	137-58-6
Density	1.026 g/cm³
Melting Point	66-69 °C
Boiling Point	350.8 °C at 760 mmHg
Flash Point	166 °C
Vapor Pressure	4.28E-05mmHg at 25°C
Refractive Index	1.5110 (estimate)
HS CODE	DERIVATION
PSA	32.34000
LogP	2.65670
Pka	pKa 7.88(H2O)(Approximate)

3.What are another words for Lidocaine ?

Synonyms for Lidocaine 137-58-6:2',6'-Acetoxylidide,2-(diethylamino)- (8CI);2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide;Antrolin;Cuivasil;Dalcaine;ELA-Max;Esracaine;Isicaine;Jetocaine;Leostesin;Lidocadren;Lidoderm;Linisol;Maricaine;Penles;Remicaine;Solarcaine;Solcain;Xilina;Xycaine;Xyline;Xylocaine;Xylocitin;a-Diethylamino-2,6-acetoxylidide;

4.What is the molecular formula of Lidocaine?

The chemical formula of Lidocaine is C14H22N2O which containing 14 Carbon atoms,22 Hydrogen atoms,2 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of Lidocaine is 234.341.

5.What is Lidocaine (137-58-6) used for?

Lidocaine is a widely used medication in the United States with various medical applications. It belongs to the class of local anesthetics and is employed to temporarily numb specific areas of the body, providing pain relief during medical procedures, such as dental work, minor surgeries, and various dermatological treatments.

InChI:InChI=1/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)/p+1

Relevant articles related to Lidocaine:

Article	Source
Disproportionation of lidocaine sulfate dihydrate in certain organic solvents.	McKenzie , p. 1297 - 1298 (1969)
The Clinical Pharmacology of Lidocaine as an Antiarrhythymic Drug	KEN A. COLLINSWORTH, SUMNER M. KALMAN and DONALD C. HARRISON , Circulation, Vol. 50, No. 6
Carboxyesterase polypeptides for amide coupling	- Page/Page column 65-66; 73-84, (2021/05/28)
Systemic lidocaine for neuropathic pain relief	Jianren Mao a, Lucy L Chen b , Pain Volume 87, Issue 1, 1 July 2000, Pages 7-17

6.Buy Lidocaine with the best price .

Hebei Qianglong Technology import and export Co, LTD is a Good Supplier In China of Lidocaine. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Lidocaine 137-58-6.

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