CasNo： 5875-06-9
Molecular Formula： C16H27ClN2O3
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Uses |
Proparacaine hydrochloride is a local anesthetic eye drop medication commonly used in the United States. Its primary use is in ophthalmology for its rapid and short-acting numbing effect on the surface of the eye. Ophthalmologists and eye care professionals administer Proparacaine prior to various eye procedures and examinations, such as tonometry (eye pressure measurement), foreign body removal, and some surgical interventions like cataract surgery and corneal procedures. By numbing the eye's surface, it helps alleviate discomfort and reduce the patient's blink reflex during these procedures, making them more manageable and less painful for the individual undergoing the examination or surgery. |
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Brand name |
Alcaine (Alcon); Ophthetic (Allergan); Paracaine (Optopics). |
InChI:InChI=1/C16H26N2O3.ClH/c1-4-10-20-15-8-7-13(12-14(15)17)16(19)21-11-9-18(5-2)6-3;/h7-8,12H,4-6,9-11,17H2,1-3H3;1H
To determine the duration of effect and the effect of multiple doses of topical ophthalmic application of 0.5% proparacaine hydrochloride on corneal sensitivity in clinically normal dogs. Duration of corneal anesthetic effect induced by topical ophthalmic application of 0.5% proparacaine in dogs of this study is considerably longer than that reported elsewhere.
Following baseline CTT measurement, 0.2 mL of 0.5% proparacaine hydrochloride was instilled in the selected eye. The CTT was measured within 1 minute following proparacaine administration and every 5 minutes thereafter for 60 minutes.
β-cyclodextrin