• N-(2,6-dimethylphenyl)-piperidine-2- carboxylic amide

N-(2,6-dimethylphenyl)-piperidine-2- carboxylic amide

  • CasNo:15883-20-2
  • Purity:99%

Product Details;

CasNo: 15883-20-2

Molecular Formula: C14H20N2O

Appearance: Off-white to light yellow powder

Reasonable Price Best Price N-(2,6-dimethylphenyl)-piperidine-2- carboxylic amide 15883-20-2 Lowest Price

  • Molecular Formula:C14H20N2O
  • Molecular Weight:232.326
  • Appearance/Colour:Off-white to light yellow powder 
  • Melting Point:114-117 ºC 
  • Boiling Point:392.3 ºC at 760 mmHg 
  • PKA:14.85±0.70(Predicted) 
  • Flash Point:149 ºC 
  • PSA:41.13000 
  • Density:1.087 g/cm3 
  • LogP:2.78580 

2',6'-Pipecoloxylidide(Cas 15883-20-2) Usage

Chemical Properties

White to Off-White

Uses

A major metabolite of Bupivacaine

Consumer Uses

ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

15883-20-2 Relevant articles

Design of an integrated process of chromatography, crystallization and racemization for the resolution of 2′,6′-pipecoloxylidide (PPX)

Von Langermann, Jan,Kaspereit, Malte,Shakeri, Mozaffar,Lorenz, Heike,Hedberg, Martin,Jones, Matthew J.,Larson, Kerstin,Herschend, Bjoern,Arnell, Robert,Temmel, Erik,Baeckvall, Jan-Erling,Kienle, Achim,Seidel-Morgenstern, Andreas

, p. 343 - 352 (2012)

An integrated process for the chiral sep...

Synthesis, biological evaluation, and molecular docking of ropivacaine analogs as local anesthetic agents

Li, Wen,Ding, Lina,Liu, Hong-Min,You, Qidong

, p. 954 - 965 (2017/11/29)

Two series of ropivacaine analogs (4a–4q...

Preparation method of bupivacaine hydrochloride

-

, (2018/01/12)

The invention discloses a preparation me...

Synthesis of Mepivacaine and Its Analogues by a Continuous-Flow Tandem Hydrogenation/Reductive Amination Strategy

Suveges, Nícolas S.,de Souza, Rodrigo O. M. A.,Gutmann, Bernhard,Kappe, C. Oliver

, p. 6511 - 6517 (2017/12/02)

Herein we report a convenient, fast, and...

Topalgia treatment methods and compositions for treating

-

Paragraph 0093; 0095, (2017/02/23)

The invention relates to the compounds o...

15883-20-2 Process route

[Cbz-piperidine-2-carboxylic acid (2,6-dimethyl-phenyl)-amide]

[Cbz-piperidine-2-carboxylic acid (2,6-dimethyl-phenyl)-amide]

2',6'-pipecoloxylidide
15883-20-2,27262-40-4,27262-43-7,78341-12-5

2',6'-pipecoloxylidide

Conditions
Conditions Yield
With hydrogen; palladium on activated carbon; In methanol; for 0.5h;
92%
palladium-carbon; In methanol;
92%
With palladium on activated charcoal; hydrogen; In methanol; at 50 ℃; for 0.5h; Autoclave;
92.1%
2-pyridine-carboxamide-N-(2,6-dimethylphenyl)
39627-98-0

2-pyridine-carboxamide-N-(2,6-dimethylphenyl)

2',6'-pipecoloxylidide
15883-20-2,27262-40-4,27262-43-7,78341-12-5

2',6'-pipecoloxylidide

Conditions
Conditions Yield
With hydrogen; nickel; acetic acid; In methanol; at 50 ℃; under 13446.2 Torr; Product distribution / selectivity;
72%
With hydrogen; acetic acid; In methanol; at 50 ℃; under 13446.2 Torr; Sealed tube;
72%
With hydrogen; acetic acid; In methanol; at 50 ℃; under 13446.2 Torr;
72%
With hydrogenchloride; platinum; Hydrogenation;

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15883-20-2 Downstream products

  • 27262-39-1
    27262-39-1

    (S)-dibenzoyl-2-pipecolinoxylidide-L-tartrate

  • 27262-40-4
    27262-40-4

    (S)-2',6'-pipecoloxylidide

  • 1364698-38-3
    1364698-38-3

    (R,S)-N-(2,6-dimethylphenyl)piperidinium-2-carboxamide bis-(trifluoromethylsulfonyl)imide

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